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Central Nervous System Processing of Human Visceral Pain in Health and Disease

Anthony R. Hobson^1,2 and Qasim Aziz¹

¹ Section of Gastrointestinal Sciences, University of Manchester, Hope Hospital, Salford M6 8HD; and
² Neurosciences Research Institute, Aston University, Birmingham B4 7ET, United Kingdom
To understand the pathophysiology of anomalous pain in functional gastrointestinal disorders, we must increase our understanding of how the central nervous system processes visceral pain. Over the past decade, novel application of functional brain imaging and electrophysiological techniques has given us the opportunity to study these processes in humans, and this review summarizes the current body of knowledge.

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