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News Physiol Sci 18: 151-157, 2003; doi:10.1152/nips.01438.2003
1548-9213/03 $5.00
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News in Physiological Sciences, Vol. 18, No. 4, 151-157, August 2003
© 2003 Int. Union Physiol. Sci./Am. Physiol. Soc.

Pulmonary Surfactant: The Key to the Evolution of Air Breathing

Christopher B. Daniels and Sandra Orgeig

Department of Environmental Biology, University of Adelaide, Adelaide, South Australia 5005, Australia
Pulmonary surfactant controls the surface tension at the air-liquid interface within the lung. This system had a single evolutionary origin that predates the evolution of the vertebrates and lungs. The lipid composition of surfactant has been subjected to evolutionary selection pressures, particularly temperature, throughout the evolution of the vertebrates.




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