Physiology Cambridge Electronic Design Limited
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

News Physiol Sci 19: 16-21, 2004; doi:10.1152/nips.01450.2003
1548-9213/04 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (24)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Borsig, L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Borsig, L.
News in Physiological Sciences, Vol. 19, No. 1, 16-21, February 2004
© 2004 Int. Union Physiol. Sci./Am. Physiol. Soc.

Selectins Facilitate Carcinoma Metastasis and Heparin Can Prevent Them

Lubor Borsig

Institute of Physiology, University of Zürich, CH-8057 Zürich, Switzerland
Selectins are cell adhesion molecules mediating attachment of leukocytes to activated endothelium as well as the adhesion reaction of tumors during malignancy. Heparin, which is known to attenuate metastasis, is a potent blocker of selectins. Here, the role of selectins in metastasis and the potential of heparin to modulate malignancy are discussed.




This article has been cited by other articles:


Home page
 J. Biol. Chem.Home page
S. N. Thomas, F. Zhu, R. L. Schnaar, C. S. Alves, and K. Konstantopoulos
Carcinoembryonic Antigen and CD44 Variant Isoforms Cooperate to Mediate Colon Carcinoma Cell Adhesion to E- and L-selectin in Shear Flow
J. Biol. Chem., June 6, 2008; 283(23): 15647 - 15655.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
S. L. Napier, Z. R. Healy, R. L. Schnaar, and K. Konstantopoulos
Selectin Ligand Expression Regulates the Initial Vascular Interactions of Colon Carcinoma Cells: THE ROLES OF CD44V AND ALTERNATIVE SIALOFUCOSYLATED SELECTIN LIGANDS
J. Biol. Chem., February 9, 2007; 282(6): 3433 - 3441.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. M. Burdick, J. T. Chu, S. Godar, and R. Sackstein
HCELL Is the Major E- and L-selectin Ligand Expressed on LS174T Colon Carcinoma Cells
J. Biol. Chem., May 19, 2006; 281(20): 13899 - 13905.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
H. Laubli, J. L. Stevenson, A. Varki, N. M. Varki, and L. Borsig
L-Selectin Facilitation of Metastasis Involves Temporal Induction of Fut7-Dependent Ligands at Sites of Tumor Cell Arrest
Cancer Res., February 1, 2006; 66(3): 1536 - 1542.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online
Copyright © 2004 by the Int. Union Physiol. Sci./Am. Physiol. Soc.