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News Physiol Sci 19: 55-60, 2004; doi:10.1152/nips.01469.2003
1548-9213/04 $5.00
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News in Physiological Sciences, Vol. 19, No. 2, 55-60, April 2004
© 2004 Int. Union Physiol. Sci./Am. Physiol. Soc.

Comparative Physiology of Lung Complexity: Implications for Gas Exchange

Frank L. Powell1,2 and Susan R. Hopkins1

1 Physiology Division, Department of Medicine, and
2 White Mountain Research Station, University of California-San Diego, La Jolla, California 92037-0623
Lungs evolved to increase diffusing capacity by compartmentalizing and reducing the size of individual gas exchange units. This increased the potential for gas exchange limitations from ventilation-perfusion heterogeneity. However, comparative studies on reptiles, birds, and mammals show that heterogeneity is independent of lung complexity.




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