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News Physiol Sci 19: 61-66, 2004; doi:10.1152/nips.01501.2003
1548-9213/04 $5.00
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News in Physiological Sciences, Vol. 19, No. 2, 61-66, April 2004
© 2004 Int. Union Physiol. Sci./Am. Physiol. Soc.

Molecular Mechanisms of Epithelial Polarity: About Shapes, Forces, and Orientation Problems

Ruth Kroschewski

Institute of Biochemistry, Swiss Federal Institute of Technology Zürich, 8093 Zürich, Switzerland
In a variety of organs, epithelial cells assemble into networks of cysts and tubules. Such structures can be reproduced in vitro. Here the importance of plasma membrane compartmentalization and forces that drive morphogenetic events during cystogenesis are discussed.




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