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Proteomic Strategies and Their Application in Studies of Renal Function

Pedro Cutillas^1,2, Alma Burlingame¹ and Robert Unwin²

¹ Ludwig Institute for Cancer Research and Department of Biochemistry, University College London, W1W 7BS, and
² Centre for Nephrology and Departments of Medicine and Physiology, Royal Free and University College Medical School, University College London, fNW3 2PF, United Kingdom
Proteomics is a promising new tool for functional genomics. In addition to two-dimensional gel electrophoresis, other methods that are based on liquid chromatography and mass spectrometry are now available to study proteins. In this brief article, we review the strengths and limitations of the proteomic approaches currently available to the researcher, and we provide examples of how proteomics has been, and can in the future be, used to study the kidney.

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				M. G. Janech, J. R. Raymond, and J. M. Arthur Proteomics in renal research Am J Physiol Renal Physiol, February 1, 2007; 292(2): F501 - F512. [Abstract] [Full Text] [PDF]