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Physiology 19: 322-325, 2004; doi:10.1152/physiol.00030.2004
1548-9213/04 $5.00
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Physiology, Vol. 19, No. 6, 322-325, December 2004
© 2004 Int. Union Physiol. Sci./Am. Physiol. Soc.

EMERGING TECHNOLOGIES

Imaging Takes a Quantum Leap

Diane S. Lidke and Donna J. Arndt-Jovin

Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, D-37077 Göttingen, Germany

dlidke{at}gwdg.de

Semiconducting nanocrystals, or quantum dots (QDs), have emerged as a new tool in physiological imaging, combining high brilliance, photostability, broad excitation but very narrow emission spectra, and surface chemistry compatible with biomolecular conjugation. In this review, we demonstrate the power of QDs in diverse applications, including long-term in vivo fluorescence imaging.






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