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News in Physiological Sciences, Vol 2, 16-18, Copyright © 1987 by International Union of Physiological Sciences
ARTICLES |
C Crone
Capillary permeability is usually ascribed to a number of "small" pores. In this article the small-pore pathway is identified as interruptions in the tight junctions between endothelial cells. Modulation of capillary permeability involves control of tight junction permeability with cytosolic Ca2+ as the important signal molecule. Actin and myosin filaments are probably involved in the process, which may implicate subtle changes in cell shape.
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