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News Physiol Sci 2: 22-26, 1987;
1548-9213/87 $5.00
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News in Physiological Sciences, Vol 2, 22-26, Copyright © 1987 by International Union of Physiological Sciences

ARTICLES

Fluid Absorption in the Kidney Proximal Tubule

JA Schafer

Fluid absorption in the proximal tubule can be driven by a small osmotic difference between the luminal and interstitial fluids because this leaky epithelium has a high water permeability. The osmotic difference is produced by solute absorption, which tends to dilute the luminal fluid and concentrate the interstitial fluid. However, important questions remain unanswered regarding the pathway for water flow and the role of hemodynamic and humoral factors.




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