Physiology Journal of Applied Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

News Physiol Sci 2: 97-100, 1987;
1548-9213/87 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Simionescu, M.
Right arrow Articles by Simionescu, N.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Simionescu, M.
Right arrow Articles by Simionescu, N.

News in Physiological Sciences, Vol 2, 97-100, Copyright © 1987 by International Union of Physiological Sciences

ARTICLES

How Plasma Macromolecules Cross the Endothelium

M Simionescu, L Ghitescu, A Fixman and N Simionescu

Plasma macromolecules can, in some tissues, cross the capillary wall and enter the interstitial space by a specific mechanism of transcytosis in which a macromolecule is first recognized by its receptor on the luminal surface of endothelial cells. A cluster of receptors bearing their cargo is confined to a vesicle that crosses the cells and discharges the macromolecules on the abluminal surface. The process may be especially important for transport of large molecules, such as albumin, transferrin, insulin, and low-density-lipoprotein, to the cells where they are needed.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
D. T. Le, P. Borgs, T. W. Toneff, M. H. Witte, and S. I. Rapaport
Hemostatic factors in rabbit limb lymph: relationship to mechanisms regulating extravascular coagulation
Am J Physiol Heart Circ Physiol, March 1, 1998; 274(3): H769 - H776.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online