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Physiology 20: 180-193, 2005; doi:10.1152/physiol.00001.2005
1548-9213/05 $8.00
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Physiology, Vol. 20, No. 3, 180-193, June 2005
© 2005 Int. Union Physiol. Sci./Am. Physiol. Soc.

REVIEW

Development of Structures and Transport Functions in the Mouse Placenta

Erica D. Watson and James C. Cross

Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada

jcross{at}ucalgary.ca

The placenta is essential for sustaining the growth of the fetus during gestation, and defects in its function result in fetal growth restriction or, if more severe, fetal death. Several molecular pathways have been identified that are essential for development of the placenta, and mouse mutants offer new insights into the cell biology of placental development and physiology of nutrient transport.




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