Physiology Cambridge Electronic Design Limited
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Physiology 20: 408-416, 2005; doi:10.1152/physiol.00031.2005
1548-9213/05 $8.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (20)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Jespersen, T.
Right arrow Articles by Olesen, S.-P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Jespersen, T.
Right arrow Articles by Olesen, S.-P.
Physiology, Vol. 20, No. 6, 408-416, December 2005
© 2005 Int. Union Physiol. Sci./Am. Physiol. Soc.

REVIEW

The KCNQ1 Potassium Channel: From Gene to Physiological Function

Thomas Jespersen1, Morten Grunnet1,2 and Søren-Peter Olesen1,2

1 Department of Medical Physiology and Danish Arrhythmia Research Center, The Panum Institute, University of Copenhagen, Copenhagen, Denmark, and
2 NeuroSearch, Ballerup, Denmark

The voltage-gated KCNQ1 (KvLQT1, Kv7.1) potassium channel plays a crucial role in shaping the cardiac action potential as well as in controlling the water and salt homeostasis in several epithelial tissues. KCNQ1 channels in these tissues are tightly regulated by auxiliary proteins and accessory factors, capable of modulating the properties of the channel complexes. This paper reviews the current knowledge about the KCNQ1 channel with a major focus on interacting proteins and physiological functions.




This article has been cited by other articles:


Home page
 Am. J. Physiol. Gastrointest. Liver Physiol.Home page
P. J. Bajwa, A. Alioua, J. W. Lee, D. S. Straus, L. Toro, and C. Lytle
Fenofibrate inhibits intestinal Cl secretion by blocking basolateral KCNQ1 K+ channels
Am J Physiol Gastrointest Liver Physiol, December 1, 2007; 293(6): G1288 - G1299.
[Abstract] [Full Text] [PDF]

Home page
 Cardiovasc ResHome page
T. Jespersen, M. Membrez, C. S. Nicolas, B. Pitard, O. Staub, S.-P. Olesen, I. Baro, and H. Abriel
The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family
Cardiovasc Res, April 1, 2007; 74(1): 64 - 74.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online
Copyright © 2005 by the Int. Union Physiol. Sci./Am. Physiol. Soc.