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Physiology 21: 19-28, 2006; doi:10.1152/physiol.00034.2005
1548-9213/06 $8.00
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Physiology, Vol. 21, No. 1, 19-28, February 2006
© 2006 Int. Union Physiol. Sci./Am. Physiol. Soc.

REVIEW

Strategies for Developing Therapeutic Application of Human Embryonic Stem Cells

Sudhanshu P. Raikwar1, Thomas Mueller1 and Nicholas Zavazava1,2

1 Department of Internal Medicine and Veterans Affairs Medical Center, and
2 Interdisciplinary Immunology Program, University of Iowa, Iowa City, Iowa

nicholas-zavazava{at}uiowa.edu

The ongoing debate on human embryonic stem cells (hESC) is fuelled by ethical concerns but also by the legitimate hope that hESC could one day be used for the cure of presently untreatable human diseases. Here we discuss current approaches to and constraints upon hESC differentiation and describe their potential application in clinical medicine.




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