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Physiology 21: 69-78, 2006; doi:10.1152/physiol.00040.2005
1548-9213/06 $8.00
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Physiology, Vol. 21, No. 1, 69-78, February 2006
© 2006 Int. Union Physiol. Sci./Am. Physiol. Soc.

REVIEW

Calcium-Activated Potassium Channels and the Regulation of Vascular Tone

Jonathan Ledoux, Matthias E. Werner, Joseph E. Brayden and Mark T. Nelson

Department of Pharmacology, College of Medicine, University of Vermont, Burlington, Vermont

mark.nelson{at}uvm.edu

Different calcium signals in the endothelium and smooth muscle target different types of Ca2+-sensitive K+ channels to modulate vascular function. These differential calcium signals and targets represent multilayered opportunities for prevention and/or treatment of vascular dysfunctions.




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