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Physiology 21: 146-152, 2006; doi:10.1152/physiol.00049.2005
1548-9213/06 $8.00
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Physiology, Vol. 21, No. 2, 146-152, April 2006
© 2006 Int. Union Physiol. Sci./Am. Physiol. Soc.

REVIEW

Vasopressin and Pair-Bond Formation: Genes to Brain to Behavior

Hemanth P. Nair and Larry J. Young

Department of Psychiatry, Center for Behavioral Neuroscience, Yerkes National Primate Center, Emory, University, Atlanta, Georgia

Microtine rodents provide an excellent model for the study of the neurobiology of social bonds. In this review, we discuss how the presence of a microsatellite sequence in the prairie vole vasopressin receptor gene may determine vasopressin receptor binding patterns in the brain and how these patterns may in turn affect social behavior.




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