Physiology AJP: Endocrinology and Metabolism
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Physiology 21: 233-241, 2006; doi:10.1152/physiol.00010.2006
1548-9213/06 $8.00
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Physiology, Vol. 21, No. 4, 233-241, August 2006
© 2006 Int. Union Physiol. Sci./Am. Physiol. Soc.

EMERGING TECHNOLOGIES

(De)constructing Mitochondria: What For?

Kai S. Dimmer and Luca Scorrano

Dulbecco-Telethon Institute, Venetian Institute of Molecular Medicine, I-35129 Padova, Italy, luca.scorrano{at}unipd.it

Mitochondria are dynamic organelles, essential for cell life and death. The morphology of this organelle is determined by fusion and fission, controlled by a growing set of "mitochondria-shaping" proteins, which influence crucial signalling cascades, including apoptosis.






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