HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Web of Science (4) Citing Articles via Google Scholar Google Scholar Articles by Hibino, H. Articles by Kurachi, Y. Search for Related Content PubMed PubMed Citation Articles by Hibino, H. Articles by Kurachi, Y.

REVIEW

Molecular and Physiological Bases of the K⁺ Circulation in the Mammalian Inner Ear

Hiroshi Hibino and Yoshihisa Kurachi

Department of Pharmacology, Division of Molecular and Cellular Pharmacology, Graduate School of Medicine, Osaka University, Osaka, Japan, ykurachi{at}pharma2.med.osaka-u.ac.jp

Endolymph, the extracellular solution in cochlea, contains 150 mM K⁺ and exhibits a potential of approximately +80 mV relative to neighboring extracellular spaces. This unique situation, essential for hearing, is maintained by K⁺ circulation from perilymph to endolymph through the cochlear lateral wall. Recent studies have identified ion-transport molecules involved in the K⁺ circulation and their pathophysiological relevance.