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Physiology 22: 234-240, 2007; doi:10.1152/physiol.00011.2007
1548-9213/07 $8.00
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Physiology, Vol. 22, No. 4, 234-240, August 2007
© 2007 Int. Union Physiol. Sci./Am. Physiol. Soc.

REVIEW

Facilitated Hexose Transporters: New Perspectives on Form and Function

Andrei R. Manolescu, Kate Witkowska, Adam Kinnaird, Tara Cessford and Chris Cheeseman

Membrane Protein Research Group, Department of Physiology, University of Alberta, Edmonton, Alberta, Canada chris.cheeseman{at}ualberta.ca

The recent sequencing of the human genome has resulted in the addition of nine new hGLUT isoforms to the SLC2A family, many of which have widely varying substrate specificity, kinetic behavior, and tissue distribution. This review examines some new hypotheses related to the structure and function of these proteins.







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