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REVIEW
1 Department of Biomedical Sciences, University of Padova,
2 Consiglio Nazionale delle Ricerche (CNR) Institute of Neurosciences,
3 Venetian Institute of Molecular Medicine (VIMM), and
4 Dulbecco Telethon Institute, Padova, Italy stefano.schiaffino{at}unipd.it
A variety of fiber types with different contractile and metabolic properties is present in mammalian skeletal muscle. The fiber-type profile is controlled by nerve activity via specific signaling pathways, whose identification may provide potential therapeutic targets for the prevention and treatment of metabolic and neuromuscular diseases.
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