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Physiology 22: 279-286, 2007; doi:10.1152/physiol.00007.2007
1548-9213/07 $8.00
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Physiology, Vol. 22, No. 4, 279-286, August 2007
© 2007 Int. Union Physiol. Sci./Am. Physiol. Soc.

REVIEW

Optimization of Single-Photon Response Transmission at the Rod-to-Rod Bipolar Synapse

Haruhisa Okawa3 and Alapakkam P. Sampath1,2,3

1 Zilkha Neurogenetic Institute,
2 Department of Physiology and Biophysics,
3 Neuroscience Graduate Program, University of Southern California, Los Angeles, California asampath{at}usc.edu

Our ability to see in dim light is limited by the statistics of light absorption in rod photoreceptors and the faithful transmission of the light-evoked signals through the retina. This article reviews the physiological mechanisms at the synapse between rods and rod bipolar cells, the first relay in a pathway that mediates vision near absolute threshold.






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Copyright © 2007 by the Int. Union Physiol. Sci./Am. Physiol. Soc.