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Physiology 23: 75-83, 2008; doi:10.1152/physiol.00047.2007
1548-9213/08 $8.00
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Physiology, Vol. 23, No. 2, 75-83, April 2008
© 2008 Int. Union Physiol. Sci./Am. Physiol. Soc.

REVIEW

Neural Systems Controlling the Drive to Eat: Mind Versus Metabolism

Huiyuan Zheng and Hans-Rudi Berthoud

Neurobiology of Nutrition Laboratory, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana berthohr{at}pbrc.edu

With the bleak outlook that 75% of Americans will be overweight or obese in 10 years, it is essential to find efficient help very soon. Knowledge of the powerful and complex neural systems conferring the basic drive to eat is a prerequisite for designing efficient therapies. Recent studies suggest that the cross talk between brain areas involved in cognitive, emotional, and metabolic-regulatory functions may explain why energy homeostasis breaks down for many predisposed individuals in our modern environment.






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