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REVIEW

Brain Protection by Erythropoietin: A Manifold Task

Tamer Rabie and Hugo H. Marti

Institute of Physiology and Pathophysiology, University of Heidelberg, Heidelberg, Germany hugo.marti{at}physiologie.uni-hd.de

Many hematopoietic growth factors are produced locally in the brain. Among these, erythropoietin (Epo), has a dominant role for neuroprotection, neurogenesis, and acting as a neurotrophic factor in the central nervous system. These functions make erythropoietin a good candidate for treating diseases associated with neuronal cell death.

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