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REVIEW
Department of Neuroscience, University of Connecticut Medical School, Farmington, Connecticut, bansal{at}neuron.uchc.edu
The myelin sheath is an extension of the oligoddendrocyte (OL) plasma membrane enriched in lipids that ensheaths the axons of the central and peripheral nervous system. Here, we review the involvement of glycosphingolipids in myelin/OL functions, including the regulation of OL differentiation, lipid raft-mediated trafficking and signaling, and neuronglia interactions.
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