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News Physiol Sci 3: 17-20, 1988;
1548-9213/88 $5.00
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News in Physiological Sciences, Vol 3, 17-20, Copyright © 1988 by International Union of Physiological Sciences

ARTICLES

Renal Calcium Transport: Sites and Insights

PA Friedman

In the kidney the absorption of calcium in the proximal tubule is mediated largely through passive transport processes, in the distal tubule by hormone-sensitive transcellular movement, whereas the loop on Henle represents a hybrid situation. The ability of calcium-transporting cells to accommodate wide ranges of transcellular movement without disturbing cytosolic calcium-dependent processes suggests the presence of mechanisms to coordinate apical entry and basolateral efflux of calcium.


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