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News Physiol Sci 3: 21-24, 1988;
1548-9213/88 $5.00
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News in Physiological Sciences, Vol 3, 21-24, Copyright © 1988 by International Union of Physiological Sciences

ARTICLES

Starvation as a Treatment of Obesity: The Need to Conserve Body Protein

Y Le Maho, J-P Robin and Y Cherel

Starvation has successfully been used to treat severe human obesity but may be dangerous due to excessive loss of body protein. Obese humans when starving use fat and spare protein as effectively as those animals that spontaneously undergo prolonged fasting after accumulating large fat reserves. Nevertheless, slow loss of protein during complete starvation may in severely obese persons lead to a cumulative protein loss that leads to sudden death before the fat reserves are depleted.


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