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News Physiol Sci 3: 61-65, 1988;
1548-9213/88 $5.00
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News in Physiological Sciences, Vol 3, 61-65, Copyright © 1988 by International Union of Physiological Sciences

ARTICLES

Renal Reabsorption of Water. Are there Pores in Proximal Tubule Cells?

G Whittembury and P Carpi-Medina

Transcellular water movement occurs mainly through water channels where water molecules move in single file. These channels, which explain the large water permeability of the proximal tubule cells, are closed by mercurial sulfhydryl reagents. There are similarities between these channels and those of human red cells and those that appear in distal nephron segments and toad urinary bladder after antidiuretic hormone stimulation.




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