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News Physiol Sci 3: 120-124, 1988;
1548-9213/88 $5.00
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News in Physiological Sciences, Vol 3, 120-124, Copyright © 1988 by International Union of Physiological Sciences

ARTICLES

Eggs, Sperm, and Sugar. A Recipe for Fertilization

PM Wassarman

The extracellular coat surrounding unfertilized mammalian eggs contains receptors that sperm recognize and bind in a species-specific manner during fertilization. These sperm receptors are glycoproteins that regulate interactions between eggs and sperm both before and after fertilization. Recent evidence suggests that it is certain of the sperm receptor's oligosaccharides that mediate gamete recognition and binding during mammalian fertilization.




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