Physiology AJP: Advances in Physiology Education
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News Physiol Sci 3: 138-144, 1988;
1548-9213/88 $5.00
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News in Physiological Sciences, Vol 3, 138-144, Copyright © 1988 by International Union of Physiological Sciences

ARTICLES

Plasma Catechols - What Do They Mean?

DS Goldstein and G Eisenhofer

Tracer pharmacokinetic techniques are more accurate than antecubital venous plasma levels for measuring sympathoneural activity using plasma norepinephrine (NE). Combined measurements of NE and dihydroxyphenylglycol can be used to estimate the rate of neuronal reuptake of endogenous NE. Plasma dihydroxyphenylalanine, derived substantially from sympathic nerve endings and the brain, may reflect the rate of catecholamine synthesis.




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