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News Physiol Sci 3: 144-147, 1988;
1548-9213/88 $5.00
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News in Physiological Sciences, Vol 3, 144-147, Copyright © 1988 by International Union of Physiological Sciences

ARTICLES

Granulocyte: Friend and Foe

W. Schmid-Schonbein G,

Circulating granulocytes play an important role in microvascular perfusion and organ pathology. Compared with red cells, granulocytes are large, stiff cells that can adhere strongly to the vascular endothelium. This may cause accumulation of granulocytes in the microcirculation and obstruct capillaries and cause cardiovascular complications. The analysis of granulocyte kinetics in the circulation has helped us better understand the etiology of a wide class of cardiovascular disease.




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