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News Physiol Sci 3: 211-216, 1988;
1548-9213/88 $5.00
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News in Physiological Sciences, Vol 3, 211-216, Copyright © 1988 by International Union of Physiological Sciences

ARTICLES

Molecular Basis of Lymphocyte-Mediated Destruction of Traget Cells

JD-E Young and ZA Cohn

Subsets of lymphocytes, known as cytotoxic T lymphocytes or natural killer cells, are potent killers of target cells. These immune cells have large granules in their cytoplasm containing cytotoxic peptides and other factors. Several of these molecules have been isolated and their functions elucidated.




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