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News Physiol Sci 4: 9-12, 1989;
1548-9213/89 $5.00
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News in Physiological Sciences, Vol 4, 9-12, Copyright © 1989 by International Union of Physiological Sciences

ARTICLES

Potential Role of Heparanase in Atherosclerosis

JH Campbell and GR Campbell

The mechanism by which a change in smooth muscle phenotype is effected in the artery wall during atherogenesis may be via release of extracellular matrix-degrading enzymes, particularly heparanase, from activated macrophages and T lymphocytes.




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