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News Physiol Sci 4: 176-181, 1989;
1548-9213/89 $5.00
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News in Physiological Sciences, Vol 4, 176-181, Copyright © 1989 by International Union of Physiological Sciences

ARTICLES

Colonic Electrical Activity: Concerto for Two Pacemakers

KM Sanders

In the proximal colon, two discrete pacemaker populations exist: one group of cells generates the 6-cycle/min rhythm known as slow waves;other cells generate a 17-cycle/min rhythm termed myenteric potential oscillations. Summation of these events in the circular muscle provides the signal for escitation-contraction coupling. This article describes the origin and integration of pacemaker activities in the colon.


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