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News Physiol Sci 5: 21-24, 1990;
1548-9213/90 $5.00
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News in Physiological Sciences, Vol 5, 21-24, Copyright © 1990 by International Union of Physiological Sciences

ARTICLES

The Role of Early Signaling Events in the Mitogenic Response

E Rozengurt and SS Ober

Mitogenic agents such as polypeptide growth factors, regulatory peptides, hormones, and pharmacological agents produce a variety of early intracellular signaling events in quiescent fibroblast cell systems. The nature of these initial events is discussed in connection with the evidence for their synergistic roles in the cellular mitogenic response.




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