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News in Physiological Sciences, Vol 6, 29-34, Copyright © 1991 by International Union of Physiological Sciences
ARTICLES |
K Wasserman, JE Hansen and DY Sue
Development of lactic acidosis is essential in performance of heavy work. H+, locally produced with lactate during inadequate O2 flow to tissues, raises capillary PO2 and facilitates O2 diffusion to mitochondria. This provides feedback control when there is imbalance between O2 requirement and supply.
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