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News Physiol Sci 6: 51-56, 1991;
1548-9213/91 $5.00
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News in Physiological Sciences, Vol 6, 51-56, Copyright © 1991 by International Union of Physiological Sciences

ARTICLES

Multiple Signal-Transduction Pathways Synergize in Platelet Activation

W Siess

At least three signal-transduction pathways are present in platelets which synergize with each other: calcium mobilization, protein kinase C activation, and an unknown pathway triggered by Gi protein activation. Each pathway can synergize with the other independently of the third pathway in the induction of platelet aggregation.


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