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News Physiol Sci 6: 119-123, 1991;
1548-9213/91 $5.00
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News in Physiological Sciences, Vol 6, 119-123, Copyright © 1991 by International Union of Physiological Sciences

ARTICLES

Presynaptic Modulation of Cholinergic and Noradrenergic Neurotransmission: Interaction Between Them

ES Vizi, J Kiss and IJ Elenkov

Ca2+-dependent, stimulation-evoked release of norepinephrine and acetylcholine from axon terminals is subject to presynaptic modulation through different receptors. These transmitters can modify their own release, and each transmitter release can be reduced by the other one. Many other compounds can also modulate this process.


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