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News Physiol Sci 6: 169-173, 1991;
1548-9213/91 $5.00
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News in Physiological Sciences, Vol 6, 169-173, Copyright © 1991 by International Union of Physiological Sciences

ARTICLES

Cell Responsiveness and Protein Kinase C: Receptors, G Proteins, and Membrane Effectors

JA Garcia-Sainz

Protein kinase C (PKC) is activated physiologically by the second messenger diacylglycerol and pharmacologically by phorbol esters. This enzyme participates in regulatory feedback loops and in cross-talk between different signal transduction systems. Among PKC substrates are receptors, G proteins, and membrane effectors.


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