Physiology AJP: Gastrointestinal and Liver Physiology
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News Physiol Sci 6: 185-190, 1991;
1548-9213/91 $5.00
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News in Physiological Sciences, Vol 6, 185-190, Copyright © 1991 by International Union of Physiological Sciences

ARTICLES

Neural Control of Cardiac Pacemaker Potentials

GDS Hirst, FR Edwards, NJ Bramich and MF Klemm

Cardiac pacemaker cells generate rhythmic discharge of action potentials. Parasympathetic activity slows, while sympathetic activity accelerates, the rate of discharge. Neuronally released transmitters activate different receptors on pacemaker cells from those activated by exogenous transmitters. Neuronally activated "junctional" receptors selectively decrease and increase inward current during diastole.




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