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News Physiol Sci 6: 206-210, 1991;
1548-9213/91 $5.00
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News in Physiological Sciences, Vol 6, 206-210, Copyright © 1991 by International Union of Physiological Sciences

ARTICLES

IGF-I, a Key Regulator of Renal Phosphate Transport and 1,25-Dihydroxyvitamin D3 Production During Growth

J Caverzasio and J-P Bonjour

During development of vertebrates the extracellular concentration of Pi and, consequently, the amount of Pi available for cellular growth and bone mineral deposition is maintained at a higher level than during adult life. Insulin-like growth factor I plays a specific role in this Pi economy.


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