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News Physiol Sci 6: 251-255, 1991;
1548-9213/91 $5.00
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News in Physiological Sciences, Vol 6, 251-255, Copyright © 1991 by International Union of Physiological Sciences

ARTICLES

The Role of Vascular Alpha-2-Adrenoceptors as Cutaneous Thermosensors

NA Flavahan

Alpha-2-Adrenoceptors are found predominantly in cutaneous arteries and veins. These receptors are responsible for the unique thermosensitivity of the cutaneous circulation, enabling it to constrict during local cooling, thereby preventing heat loss. This mechanism appears to be increased in Raynaud's disease, causing an exaggerated response to cold.


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