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News Physiol Sci 6: 265-268, 1991;
1548-9213/91 $5.00
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News in Physiological Sciences, Vol 6, 265-268, Copyright © 1991 by International Union of Physiological Sciences

ARTICLES

The Coronary Circulation: Limitations of Current Concepts of Metabolic Control

H Gewirtz

Experimental data indicate the metabolic theory of flow regulation has difficulties explaining long-term adjustments of coronary circulation to chronic hypofusion. Evidence is reviewed supporting the hypothesis that chronic adjustments could involve changes in structural or regulatory proteins participating in vascular smooth muscle contraction.




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