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News Physiol Sci 6: 281-286, 1991;
1548-9213/91 $5.00
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News in Physiological Sciences, Vol 6, 281-286, Copyright © 1991 by International Union of Physiological Sciences

ARTICLES

How the Motoneuron Regulates Acetylcholine Receptor Channel Function in Muscle

HR Brenner

Distribution and ion-conduction properties of acetylcholine receptors (AChR) in muscle change under neural control. The switch of AChR types at the synapse is regulated by neurotrophic signals. Muscle activity may support sufficient numbers of AChRs for synaptic transmission and downregulate them in nonsynaptic fiber segments.




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