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News Physiol Sci 7: 23-26, 1992;
1548-9213/92 $5.00
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News in Physiological Sciences, Vol 7, 23-26, Copyright © 1992 by International Union of Physiological Sciences


ARTICLES

Impaired Transmission of Pressure to the Renal Interstitium in Spontaneous Hypertension

AA Khraibi

In Okamoto spontaneously hypertensive rats, compared with control Wistar-Kyoto rats, natriuretic and diuretic responses to increases in renal perfusion pressure are attenuated but with acute saline volume expansion they are exaggerated. The extent of elevations in renal interstitial hydrostatic pressure appears to determine the natriuretic and diuretic responses.





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