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News Physiol Sci 7: 143-148, 1992;
1548-9213/92 $5.00
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News in Physiological Sciences, Vol 7, 143-148, Copyright © 1992 by International Union of Physiological Sciences

ARTICLES

Subcellular Localization of the Type II cAMP-Dependent Protein Kinase

JD Scott and DW Carr

Diverse biochemical effects of different neurotransmitters or hormones that stimulate cAMP production may occur through activation of compartmentalized pools of cAMP-dependent protein kinase (PKA). Evidence suggests that compartmentalization of type II PKA is maintained through protein-protein interactions between the regulatory subunit and specific anchoring proteins.




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