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News Physiol Sci 7: 152-156, 1992;
1548-9213/92 $5.00
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News in Physiological Sciences, Vol 7, 152-156, Copyright © 1992 by International Union of Physiological Sciences


ARTICLES

Communication Among Endothelial and Smooth Muscle Cells Coordinates Blood Flow Control During Exercise

SS Segal

Peripheral blood flow control during exercise is coordinated among several vascular locations. The locus of control shifts upstream from distal arterioles into feeding arteries as metabolic demand increases. This shift occurs by cell-to-cell conduction and by flow-dependent endothelial cell-mediated relaxation of smooth muscle cells.


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