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News Physiol Sci 7: 176-180, 1992;
1548-9213/92 $5.00
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News in Physiological Sciences, Vol 7, 176-180, Copyright © 1992 by International Union of Physiological Sciences

ARTICLES

Mobilization of Specific Neuropeptides by Peripheral Stimulation of Identified Frequencies

J-S Han and Q Wang

Three families of endogenous opioid peptides have been characterized in the CNS: enkephalins, endorphins and dynorphins. These can be mobilized by peripheral electrical stimulation. Stimulation at 2 Hz may accelerate the release of enkephalins and Beta-endorphin, whereas 100 Hz is most effective in releasing dynorphin.




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