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News Physiol Sci 7: 215-219, 1992;
1548-9213/92 $5.00
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News in Physiological Sciences, Vol 7, 215-219, Copyright © 1992 by International Union of Physiological Sciences

ARTICLES

Neutrophil Activation: Control of Shape Change, Exocytosis, and Respiratory Burst

M Baggiolini and P Kernen

Neutrophil leukocytes are defence cells that are recruited from the blood into inflamed tissues by chemotactic agonists. Agonist-receptor interaction elicits motion, granule exocytosis, and the respiratory burst. In vitro analysis shows that these responses are controlled at different levels of the intracellular signal transduction process.


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