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News Physiol Sci 8: 57-60, 1993;
1548-9213/93 $5.00
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News in Physiological Sciences, Vol 8, 57-60, Copyright © 1993 by International Union of Physiological Sciences

ARTICLES

Clues to the Cell-Specific Synthesis of Complex Carbohydrates

EG Berger and M Thurnher

Important functions such as cell adhesion and cell recognition depend on complex carbohydrates (glycans) whose structures are remarkably diverse. Glycans are synthesized by specific glycosyltransferases. Their expression and topogenesis to the proper Golgi subcompartment, availability of sugar nucleotides, and undisturbed intracellular traffic are critical factors of cell-specific glycosylation.


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