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News Physiol Sci 8: 91-93, 1993;
1548-9213/93 $5.00
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News in Physiological Sciences, Vol 8, 91-93, Copyright © 1993 by International Union of Physiological Sciences

ARTICLES

Epithelial Secretion Driven by Anions Other Than Chloride

DI Cook and JA Young

Exocrine glands commonly secrete salt using Na+-K+-2Cl- cotransporters to drive secondary active Cl- transport;this process is blocked by furosemide. However, secretion in some glands depends on furosemide-insensitive mechanisms. Some use a Na+-H+ exchanger to transport HCO3-;others may transport HCO3- and HPO24-.




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