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News Physiol Sci 8: 103-107, 1993;
1548-9213/93 $5.00
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News in Physiological Sciences, Vol 8, 103-107, Copyright © 1993 by International Union of Physiological Sciences

ARTICLES

Spatiotemporal Aspects of Ca2+ Signaling in Exocrine Acinar Cells

S Dissing, JL Gromada, NK Jorgensen, J Frokjaer-Jensen and B Nauntofte

Digital image processing technique on fura-2-loaded acinar cells from exocrine gland end pieces shows that, on receptor activation, intracellular free Ca2+ concentration rises rapidly at the basolateral and luminal membranes. This is consistent with a model in which K+ channels at basolateral membranes and Cl- channels at luminal membranes are activated simultaneously.




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